Cargando…
STAT3-mediated activation of miR-21 is involved in down-regulation of TIMP3 and neovascularization in the ischemic retina
Retinal neovascularization (RNV) is a sight threatening complication of ischemic retinopathies with limited therapeutic options. The transcription factor signal transducer and activator of transcription 3 (STAT3) has been shown to play a crucial role in promoting RNV. However, manipulating of STAT3...
Autores principales: | Gutsaeva, Diana R., Thounaojam, Menaka, Rajpurohit, Shubhra, Powell, Folami L., Martin, Pamela M., Goei, Stephanie, Duncan, Michael, Bartoli, Manuela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732751/ https://www.ncbi.nlm.nih.gov/pubmed/29262585 http://dx.doi.org/10.18632/oncotarget.21592 |
Ejemplares similares
-
Ursodeoxycholic Acid Halts Pathological Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy
por: Thounaojam, Menaka C., et al.
Publicado: (2020) -
Inhibition of HDAC6 Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy
por: Abouhish, Hossameldin, et al.
Publicado: (2020) -
MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities
por: Thounaojam, Menaka C., et al.
Publicado: (2019) -
Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration
por: Jadeja, Ravirajsinh N., et al.
Publicado: (2019) -
Implications of NAD(+) Metabolism in the Aging Retina and Retinal Degeneration
por: Jadeja, Ravirajsinh N., et al.
Publicado: (2020)