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Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle

Deregulation of proliferation and differentiation-dependent signalling pathways is a hallmark of human papillomavirus (HPV) infection. Although the manipulation of these pathways by E6 and E7 has been extensively studied, controversies surround the role of the E5 oncoprotein during a productive viru...

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Detalles Bibliográficos
Autores principales: Wasson, Christopher W., Morgan, Ethan L., Müller, Marietta, Ross, Rebecca L., Hartley, Margaret, Roberts, Sally, Macdonald, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732752/
https://www.ncbi.nlm.nih.gov/pubmed/29262586
http://dx.doi.org/10.18632/oncotarget.21658