Multi-omics analyses of red blood cell reveal antioxidation mechanisms associated with hemolytic toxicity of gossypol

Gossypol is an antiproliferative drug with limited use due to its hemolytic toxicity. In this study, accelerated hemolysis was observed in the cows treated with gossypol. Comparative metabolomics were used to gain responsive pathways in the red blood cell (RBC) to the treatment, which were crossly v...

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Detalles Bibliográficos
Autores principales: Tang, Chaohua, Meng, Qingshi, Zhang, Kai, Zhan, Tengfei, Zhao, Qingyu, Zhang, Sheng, Zhang, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732760/
https://www.ncbi.nlm.nih.gov/pubmed/29262594
http://dx.doi.org/10.18632/oncotarget.21779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732760/
https://www.ncbi.nlm.nih.gov/pubmed/29262594
http://dx.doi.org/10.18632/oncotarget.21779

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