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Multi-omics analyses of red blood cell reveal antioxidation mechanisms associated with hemolytic toxicity of gossypol
Gossypol is an antiproliferative drug with limited use due to its hemolytic toxicity. In this study, accelerated hemolysis was observed in the cows treated with gossypol. Comparative metabolomics were used to gain responsive pathways in the red blood cell (RBC) to the treatment, which were crossly v...
Autores principales: | Tang, Chaohua, Meng, Qingshi, Zhang, Kai, Zhan, Tengfei, Zhao, Qingyu, Zhang, Sheng, Zhang, Junmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732760/ https://www.ncbi.nlm.nih.gov/pubmed/29262594 http://dx.doi.org/10.18632/oncotarget.21779 |
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