Cargando…

SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/β-catenin activation

Liver cancer is one of the most serious cancers all over the world. Liver tumor initiating cells (TICs) account for tumor initiation and metastasis. However, the regulatory mechanism of liver TICs remains unclear. Here we found long noncoding RNA SAMMSON is highly expressed in liver cancer and liver...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaopeng, Li, Ming, Chen, JiaLi, Dai, Hua, Wang, Liang, Xiong, Ying, Zhong, Yuanbin, Zhang, Lunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732766/
https://www.ncbi.nlm.nih.gov/pubmed/29262600
http://dx.doi.org/10.18632/oncotarget.21792