Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism

We analyzed survival effects for 15 different pairs of clinically relevant anti-cancer drugs in three iso-genic pairs of human colorectal cancer carcinoma cell lines, by applying for the first time our novel software (R package) called COMBIA. In our experiments iso-genic pairs of cell lines were us...

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Detalles Bibliográficos
Autores principales: Kashif, Muhammad, Andersson, Claes, Mansoori, Sharmineh, Larsson, Rolf, Nygren, Peter, Gustafsson, Mats G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732778/
https://www.ncbi.nlm.nih.gov/pubmed/29262612
http://dx.doi.org/10.18632/oncotarget.21895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732778/
https://www.ncbi.nlm.nih.gov/pubmed/29262612
http://dx.doi.org/10.18632/oncotarget.21895

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