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Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway

Preeclampsia (PE) has become the leading cause of maternal and fetal morbidity and mortality in the world, which is characterized by a systemic maternal inflammatory response associated with endothelial dysfunction, hypertension, and proteinuria. The development of PE is still barely predictable and...

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Detalles Bibliográficos
Autores principales: Gu, Ying, Feng, Yaling, Yu, Jinjin, Yuan, Hua, Yin, Yongxiang, Ding, Jian, Zhao, Jun, Xu, Yaohui, Xu, Jianjuan, Che, Haisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732790/
https://www.ncbi.nlm.nih.gov/pubmed/29262624
http://dx.doi.org/10.18632/oncotarget.22017