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Deletion of resistin-like molecule-beta attenuates angiotensin II-induced abdominal aortic aneurysm

In the present study, we want to test whether deletion of resistin-like molecule-beta (RELMβ) attenuates angiotensin II (Ang II)-induced formation of abdominal aortic aneurysm (AAA). RELMβ gene expression was inhibited by siRNA both in vivo and in vitro. Apolipoprotein E-knockout (ApoE(−/−)) mice we...

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Detalles Bibliográficos
Autores principales: Meng, Xiao, Zhang, Kai, Kong, Jing, Xu, Long, An, Guipeng, Qin, Weidong, Li, Jifu, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732796/
https://www.ncbi.nlm.nih.gov/pubmed/29262630
http://dx.doi.org/10.18632/oncotarget.22042