Inhibition of HSP90 sensitizes a novel Raf/ERK dual inhibitor CY-9d in triple-negative breast cancer cells

Raf and extracellular signal-regulated kinases (ERK) are both important therapeutic targets in the mitogen-activated protein kinase (MAPK) pathway, and play crucial roles in the apoptosis resistance of breast cancer cells. In the present study, cytotoxic and apoptosis-inducing activities of the Raf/...

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Detalles Bibliográficos
Autores principales: Chen, Yujuan, Wang, Xiaoyun, Cao, Chuan, Wang, Xiaodong, Liang, Shufang, Peng, Cheng, Fu, Leilei, He, Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732798/
https://www.ncbi.nlm.nih.gov/pubmed/29262632
http://dx.doi.org/10.18632/oncotarget.22119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732798/
https://www.ncbi.nlm.nih.gov/pubmed/29262632
http://dx.doi.org/10.18632/oncotarget.22119

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