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Glucose-derived AGEs enhance human gastric cancer metastasis through RAGE/ERK/Sp1/MMP2 cascade

Advanced glycation end products (AGEs) have been reported to take part in many cancer processes. Whether AGEs contribute to gastric cancer (GC) course and the underlying mechanism are still unclear. Here, glucose-derived AGEs are detected to be accumulated in tumor tissues and blood of patients with...

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Detalles Bibliográficos
Autores principales: Deng, Ruyuan, Mo, Fengbo, Chang, Bowen, Zhang, Qi, Ran, Hui, Yang, Shuhua, Zhu, Zhiqiang, Hu, Lei, Su, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732800/
https://www.ncbi.nlm.nih.gov/pubmed/29262634
http://dx.doi.org/10.18632/oncotarget.22185