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Hepatocellular glycogenotic foci after combined intraportal pancreatic islet transplantation and knockout of the carbohydrate responsive element binding protein in diabetic mice

AIMS: The intraportal pancreatic islet transplantation (IPIT) model of diabetic rats is an insulin mediated model of hepatocarcinogenesis characterized by the induction of clear cell foci (CCF) of altered hepatocytes, which are pre-neoplastic lesions excessively storing glycogen (glycogenosis) and e...

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Detalles Bibliográficos
Autores principales: Ribback, Silvia, Sonke, Jenny, Lohr, Andrea, Frohme, Josephine, Peters, Kristin, Holm, Johannes, Peters, Michele, Cigliano, Antonio, Calvisi, Diego F., Dombrowski, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732809/
https://www.ncbi.nlm.nih.gov/pubmed/29262643
http://dx.doi.org/10.18632/oncotarget.22234