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Inhibition of microRNA-218 reduces HIF-1α by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxia

OBJECTIVE: To investigate the effects of miR-218 on expression of hypoxia-inducible factors 1α (HIF-1α), vascular endothelial growth factor (VEGF) and cell apoptosis in normal mice aortic endothelial cells under intermittent hypoxia (IH) condition. METHODS: Anti-miR-218 inhibitor, miR-negative contr...

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Detalles Bibliográficos
Autores principales: Liu, Kai-Xiong, Chen, Qin, Chen, Gong-Ping, Huang, Jian-Chai, Huang, Jie-Feng, He, Xin-Ru, Lin, Ting, Lin, Qi-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732812/
https://www.ncbi.nlm.nih.gov/pubmed/29262646
http://dx.doi.org/10.18632/oncotarget.22239