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Inhibition of microRNA-218 reduces HIF-1α by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxia
OBJECTIVE: To investigate the effects of miR-218 on expression of hypoxia-inducible factors 1α (HIF-1α), vascular endothelial growth factor (VEGF) and cell apoptosis in normal mice aortic endothelial cells under intermittent hypoxia (IH) condition. METHODS: Anti-miR-218 inhibitor, miR-negative contr...
Autores principales: | Liu, Kai-Xiong, Chen, Qin, Chen, Gong-Ping, Huang, Jian-Chai, Huang, Jie-Feng, He, Xin-Ru, Lin, Ting, Lin, Qi-Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732812/ https://www.ncbi.nlm.nih.gov/pubmed/29262646 http://dx.doi.org/10.18632/oncotarget.22239 |
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