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Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells

Piplartine (piperlongumine) is a plant-derived molecule that has been receiving intense interest due to its anticancer characteristics that target the oxidative stress. In the present paper, two novel piplartine-containing ruthenium complexes [Ru(piplartine)(dppf)(bipy)](PF(6))(2) (1) and [Ru(piplar...

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Detalles Bibliográficos
Autores principales: D’Sousa Costa, Cinara O., Araujo Neto, João H., Baliza, Ingrid R.S., Dias, Rosane B., Valverde, Ludmila de F., Vidal, Manuela T.A., Sales, Caroline B.S., Rocha, Clarissa A.G., Moreira, Diogo R.M., Soares, Milena B.P., Batista, Alzir A., Bezerra, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732813/
https://www.ncbi.nlm.nih.gov/pubmed/29262647
http://dx.doi.org/10.18632/oncotarget.22248