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Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells
Piplartine (piperlongumine) is a plant-derived molecule that has been receiving intense interest due to its anticancer characteristics that target the oxidative stress. In the present paper, two novel piplartine-containing ruthenium complexes [Ru(piplartine)(dppf)(bipy)](PF(6))(2) (1) and [Ru(piplar...
Autores principales: | D’Sousa Costa, Cinara O., Araujo Neto, João H., Baliza, Ingrid R.S., Dias, Rosane B., Valverde, Ludmila de F., Vidal, Manuela T.A., Sales, Caroline B.S., Rocha, Clarissa A.G., Moreira, Diogo R.M., Soares, Milena B.P., Batista, Alzir A., Bezerra, Daniel P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732813/ https://www.ncbi.nlm.nih.gov/pubmed/29262647 http://dx.doi.org/10.18632/oncotarget.22248 |
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