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ETS1, nucleolar and non-nucleolar TERT expression in nevus to melanoma progression

TERT (telomerase reverse transcriptase) is the catalytic component of telomerase. TERT shows little expression in normal somatic cells but is commonly re-expressed in cancers, facilitating immortalization. Recently-discovered TERT promoter mutations create binding sites for ETS-family transcription...

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Detalles Bibliográficos
Autores principales: Kohli, Jaskaren S., Mir, Hira, Wasif, Afsheen, Chong, Heung, Akhras, Victoria, Kumar, Rajiv, Nagore, Eduardo, Bennett, Dorothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732815/
https://www.ncbi.nlm.nih.gov/pubmed/29262649
http://dx.doi.org/10.18632/oncotarget.22254