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Human CRL4(DDB2) ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56Ac through recruitment of histone chaperon CAF-1

Acetylated histone H3 lysine 56 (H3K56Ac) diminishes in response to DNA damage but is restored following DNA repair. Here, we report that CRL4(DDB2) ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56Ac through recruitment of histone chaperon CAF-1. We show that H3K5...

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Detalles Bibliográficos
Autores principales: Zhu, Qianzheng, Wei, Shengcai, Sharma, Nidhi, Wani, Gulzar, He, Jinshan, Wani, Altaf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732824/
https://www.ncbi.nlm.nih.gov/pubmed/29262658
http://dx.doi.org/10.18632/oncotarget.21869