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On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos Channels

In a healthy adult, the transport of O(2) and CO(2) between lungs and tissues is performed by about 2 · 10(13) red blood cells, of which around 1.7 · 10(11) are renewed every day, a turnover resulting from an average circulatory lifespan of about 120 days. Cellular lifespan is the result of an evolu...

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Detalles Bibliográficos
Autores principales: Lew, Virgilio L., Tiffert, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732905/
https://www.ncbi.nlm.nih.gov/pubmed/29311949
http://dx.doi.org/10.3389/fphys.2017.00977