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Metabolism of Dopamine in Nucleus Accumbens Astrocytes Is Preserved in Aged Mice Exposed to MPTP

Parkinson disease (PD) is prevalent in elderly individuals and is characterized by selective degeneration of nigrostriatal dopamine (NSDA) neurons. Interestingly, not all dopamine (DA) neurons are affected equally by PD and aging, particularly mesolimbic (ML) DA neurons. Here, effects of aging were...

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Detalles Bibliográficos
Autores principales: Winner, Brittany M., Zhang, Harue, Farthing, McKenzie M., Karchalla, Lalitha M., Lookingland, Keith J., Goudreau, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732926/
https://www.ncbi.nlm.nih.gov/pubmed/29311899
http://dx.doi.org/10.3389/fnagi.2017.00410