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The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

The CD40–CD40L dyad is an immune checkpoint regulator that promotes both innate and adaptive immune responses and has therefore an essential role in the development of inflammatory diseases, including multiple sclerosis (MS). In MS, CD40 and CD40L are expressed on immune cells present in blood and l...

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Detalles Bibliográficos
Autores principales: Aarts, Suzanne A. B. M., Seijkens, Tom T. P., van Dorst, Koos J. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732943/
https://www.ncbi.nlm.nih.gov/pubmed/29312317
http://dx.doi.org/10.3389/fimmu.2017.01791