Cargando…
The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
The CD40–CD40L dyad is an immune checkpoint regulator that promotes both innate and adaptive immune responses and has therefore an essential role in the development of inflammatory diseases, including multiple sclerosis (MS). In MS, CD40 and CD40L are expressed on immune cells present in blood and l...
Autores principales: | Aarts, Suzanne A. B. M., Seijkens, Tom T. P., van Dorst, Koos J. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732943/ https://www.ncbi.nlm.nih.gov/pubmed/29312317 http://dx.doi.org/10.3389/fimmu.2017.01791 |
Ejemplares similares
-
Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis
por: Aarts, Suzanne ABM, et al.
Publicado: (2019) -
The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease
por: Bosmans, Laura A., et al.
Publicado: (2020) -
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation
por: Aarts, Suzanne A. B. M., et al.
Publicado: (2017) -
Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH
por: Aarts, Suzanne, et al.
Publicado: (2019) -
Th40 cells (CD4(+)CD40(+) Tcells) drive a more severe form of Experimental Autoimmune Encephalomyelitis than conventional CD4 T cells
por: Vaitaitis, Gisela M., et al.
Publicado: (2017)