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Tailoring Mathematical Models to Stem-Cell Derived Cardiomyocyte Lines Can Improve Predictions of Drug-Induced Changes to Their Electrophysiology

Human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs) have applications in disease modeling, cell therapy, drug screening and personalized medicine. Computational models can be used to interpret experimental findings in iPSC-CMs, provide mechanistic insights, and translate these find...

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Detalles Bibliográficos
Autores principales:	Lei, Chon Lok, Wang, Ken, Clerx, Michael, Johnstone, Ross H., Hortigon-Vinagre, Maria P., Zamora, Victor, Allan, Andrew, Smith, Godfrey L., Gavaghan, David J., Mirams, Gary R., Polonchuk, Liudmila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732978/ https://www.ncbi.nlm.nih.gov/pubmed/29311950 http://dx.doi.org/10.3389/fphys.2017.00986

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