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Inhibition of Mitochondrial Division Attenuates Cisplatin-Induced Toxicity in the Neuromast Hair Cells

Cisplatin and other related platinum antineoplastic drugs are commonly used in the treatment of a variety of cancers in both adults and children but are often associated with severe side effects, including hearing loss. Cisplatin’s ototoxic effects are multifaceted, culminating in irreversible damag...

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Detalles Bibliográficos
Autores principales: Vargo, Jonathon W., Walker, Steven N., Gopal, Suhasini R., Deshmukh, Aditi R., McDermott Jr., Brian M., Alagramam, Kumar N., Stepanyan, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732985/
https://www.ncbi.nlm.nih.gov/pubmed/29311828
http://dx.doi.org/10.3389/fncel.2017.00393