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Netrin-1 Ameliorates Blood-Brain Barrier Impairment Secondary to Ischemic Stroke via the Activation of PI3K Pathway

Secondary impairment of blood-brain barrier (BBB) occurs in the remote thalamus after ischemic stroke. Netrin-1, an axonal guidance molecule, presents bifunctional effects on blood vessels through receptor-dependent pathways. This study investigates whether netrin-1 protects BBB against secondary in...

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Detalles Bibliográficos
Autores principales: Yu, Jian, Li, Chenguang, Ding, Qiao, Que, Jiali, Liu, Kejia, Wang, Haoyue, Liao, Songjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732993/
https://www.ncbi.nlm.nih.gov/pubmed/29311781
http://dx.doi.org/10.3389/fnins.2017.00700