Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis

Cancer cachexia is a kind of whole body metabolic disorder syndrome accompanied with severe wasting of muscle and adipose tissue. NF-κB signaling plays an important role during skeletal muscle atrophy and fat lipolysis. As an inhibitor of NF-κB signaling, Pyrrolidine dithiocarbamate (PDTC) was repor...

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Detalles Bibliográficos
Autores principales: Miao, Chunxiao, Lv, Yuanyuan, Zhang, Wanli, Chai, Xiaoping, Feng, Lixing, Fang, Yanfen, Liu, Xuan, Zhang, Xiongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733020/
https://www.ncbi.nlm.nih.gov/pubmed/29311924
http://dx.doi.org/10.3389/fphar.2017.00915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733020/
https://www.ncbi.nlm.nih.gov/pubmed/29311924
http://dx.doi.org/10.3389/fphar.2017.00915

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