Cargando…

Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis

Cancer cachexia is a kind of whole body metabolic disorder syndrome accompanied with severe wasting of muscle and adipose tissue. NF-κB signaling plays an important role during skeletal muscle atrophy and fat lipolysis. As an inhibitor of NF-κB signaling, Pyrrolidine dithiocarbamate (PDTC) was repor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miao, Chunxiao, Lv, Yuanyuan, Zhang, Wanli, Chai, Xiaoping, Feng, Lixing, Fang, Yanfen, Liu, Xuan, Zhang, Xiongwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733020/ https://www.ncbi.nlm.nih.gov/pubmed/29311924 http://dx.doi.org/10.3389/fphar.2017.00915

Ejemplares similares

Carnosol and its analogues attenuate muscle atrophy and fat lipolysis induced by cancer cachexia
por: Lu, Shanshan, et al.
Publicado: (2021)

Pyrrolidine Dithiocarbamate (PDTC) Inhibits DON-Induced Mitochondrial Dysfunction and Apoptosis via the NF-κB/iNOS Pathway
por: Wan, Dan, et al.
Publicado: (2018)

Pyrrolidine dithiocarbamate (PDTC) inhibits the overexpression of MCP-1 and attenuates microglial activation in the hippocampus of a pilocarpine-induced status epilepticus rat model
por: LV, RILANG, et al.
Publicado: (2014)

Short-term pyrrolidine dithiocarbamate administration attenuates cachexia-induced alterations to muscle and liver in Apc(Min/+) mice
por: Narsale, Aditi A., et al.
Publicado: (2016)

Pyrrolidine Dithiocarbamate Attenuates Paraquat-Induced Lung Injury in Rats
por: Chang, Xiuli, et al.
Publicado: (2009)

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
por: Liddell, Jeffrey R., et al.
Publicado: (2016)

GDF-15 in tumor-derived exosomes promotes muscle atrophy via Bcl-2/caspase-3 pathway
por: Zhang, Wanli, et al.
Publicado: (2022)

Bile acid metabolism dysregulation associates with cancer cachexia: roles of liver and gut microbiome
por: Feng, Lixing, et al.
Publicado: (2021)

Therapeutic effects of pyrrolidine dithiocarbamate on acute lung injury in rabbits
por: Wang, Meitang, et al.
Publicado: (2011)

Pyrrolidine Dithiocarbamate Suppresses Cutibacterium acnes-Induced Skin Inflammation
por: Shin, Jin Hak, et al.
Publicado: (2023)

Pyrrolidine Dithiocarbamate Prevents Neuroinflammation and Cognitive Dysfunction after Endotoxemia in Rats
por: Kan, Min Hui, et al.
Publicado: (2016)

Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia
por: Miao, Chunxiao, et al.
Publicado: (2021)

Pyrrolidine Dithiocarbamate Might Mitigate Radiation-Induced Heart Damage at an Early Stage in Rats
por: Wu, Yajing, et al.
Publicado: (2022)

Synergistic cytotoxic effect of sulindac and pyrrolidine dithiocarbamate against ovarian cancer cells
por: JAKUBOWSKA-MUĆKA, ANNA, et al.
Publicado: (2012)

Bidirectional Effects of Pyrrolidine Dithiocarbamate on Severe Acute Pancreatitis in a Rat Model
por: Yang, Huan, et al.
Publicado: (2019)

Pyrrolidine Dithiocarbamate Attenuates Cardiocyte Apoptosis and Ameliorates Heart Failure Following Coronary Microembolization in Rats
por: Li, Shumei, et al.
Publicado: (2019)

Regulatory mechanism of pyrrolidine dithiocarbamate is mediated by nuclear factor-κB and inhibits neutrophil accumulation in ARDS mice
por: WANG, HONGMAN, et al.
Publicado: (2014)

Unravelling the Role of Cancer Cell-Derived Extracellular Vesicles in Muscle Atrophy, Lipolysis, and Cancer-Associated Cachexia
por: Marzan, Akbar L., et al.
Publicado: (2023)

Coix seed oil ameliorates cancer cachexia by counteracting muscle loss and fat lipolysis
por: Liu, Huiquan, et al.
Publicado: (2019)

Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL
por: Tang, Jun-Hai, et al.
Publicado: (2017)

Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease
por: Ta, Michelle H. T., et al.
Publicado: (2014)

Pyrrolidine dithiocarbamate ameliorates endothelial dysfunction in thoracic aorta of diabetic rats by preserving vascular DDAH activity
por: Lu, Chang-Wu, et al.
Publicado: (2017)

Pyrrolidine Dithiocarbamate Facilitates Arsenic Trioxide Against Pancreatic Cancer via Perturbing Ubiquitin-Proteasome Pathway
por: Yu, Simin, et al.
Publicado: (2020)

Adipogenic Stimulation and Pyrrolidine Dithiocarbamate Induced Osteogenic Inhibition of Dental Pulp Stem Cells Is Countered by Cordycepin
por: Patil, Shankargouda, et al.
Publicado: (2021)

Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning
por: Han, Jun, et al.
Publicado: (2018)

Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells
por: Daniel, Kenyon G, et al.
Publicado: (2005)

Protective Effects of the Nuclear Factor Kappa B Inhibitor Pyrrolidine Dithiocarbamate on Experimental Testicular Torsion and Detorsion Injury
por: Kabay, Sahin, et al.
Publicado: (2014)

Inhibition of nuclear factor-κB signal by pyrrolidine dithiocarbamate alleviates lipopolysaccharide-induced acute lung injury
por: Yang, Hongfu, et al.
Publicado: (2017)

Predictive Factors for RAI-Refractory Disease and Short Overall Survival in PDTC
por: Kersting, David, et al.
Publicado: (2021)

Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-κB activity in autosomal dominant polycystic kidney disease cells
por: Ta, Michelle H. T., et al.
Publicado: (2015)

Determination of Chromium(III) and Chromium(VI) by Ammonium Pyrrolidine Dithiocarbamate-Methyl Isobutyl Ketone-Furnace Atomic Absorption Spectrometry
por: Subramanian, K. S.
Publicado: (1988)

Pyrrolidine Dithiocarbamate Inhibits Nuclear Factor κB and Toll-Like Receptor 4 Expression in Rats with Acute Necrotizing Pancreatitis
por: Xu, Min, et al.
Publicado: (2015)

Atractylenolide I ameliorates cancer cachexia through inhibiting biogenesis of IL‐6 and tumour‐derived extracellular vesicles
por: Fan, Meng, et al.
Publicado: (2022)

Novel noncoding RNA CircPTK2 regulates lipolysis and adipogenesis in cachexia
por: Ding, Zuoyou, et al.
Publicado: (2021)

Ammonium Pyrrolidine Dithiocarbamate-Modified CdTe/CdS Quantum Dots as a Turn-on Fluorescent Sensor for Detection of Trace Cadmium Ions
por: Yin, Yuan, et al.
Publicado: (2020)

PDTC Alleviates Depressive Symptoms and Colon Tissue Injury via Inhibiting NO Overproduction in CUMS Rats
por: Yang, Lejin, et al.
Publicado: (2019)

Repurposing of Antibiotic Sulfisoxazole Inhibits Lipolysis in Pre-Clinical Model of Cancer-Associated Cachexia
por: Chitti, Sai V., et al.
Publicado: (2021)

Fat Busters: Lipolysis for Face and Neck
por: Talathi, Abhay, et al.
Publicado: (2018)

The Versatility in the Applications of Dithiocarbamates
por: Ajiboye, Timothy O., et al.
Publicado: (2022)

Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia
por: Francioli, Cyril, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3a2u181ijuivuq1frf4e7qg5jd