Modulation of miR-26a-5p and miR-15b-5p Exosomal Expression Associated with Clopidogrel-Induced Hepatotoxicity in HepG2 Cells

Clopidogrel is an essential antiplatelet drug used to prevent thrombosis complications associated with atherosclerosis. However, hepatotoxicity is a potential adverse effect related to clopidogrel therapy. Exosome-derived miRNAs may be useful for improved monitoring of drug response and hepatotoxici...

Descripción completa

Detalles Bibliográficos
Autores principales: de Freitas, Renata C. Costa, Bortolin, Raul H., Lopes, Mariana B., Tamborlin, Letícia, Meneguello, Letícia, Silbiger, Vivian N., Hirata, Rosario D. C., Hirata, Mário H., Luchessi, Augusto D., Luchessi, André D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733064/
https://www.ncbi.nlm.nih.gov/pubmed/29311920
http://dx.doi.org/10.3389/fphar.2017.00906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733064/
https://www.ncbi.nlm.nih.gov/pubmed/29311920
http://dx.doi.org/10.3389/fphar.2017.00906

Ejemplares similares