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Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes

In addition to evolutionarily-accrued sequence mutation or deletion, endogenous retroelements (EREs) in eukaryotic genomes are subject to epigenetic silencing, preventing or reducing their transcription, particularly in the germplasm. Nevertheless, transcriptional activation of EREs, including endog...

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Detalles Bibliográficos
Autores principales: Attig, Jan, Young, George R., Stoye, Jonathan P., Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733090/
https://www.ncbi.nlm.nih.gov/pubmed/29312197
http://dx.doi.org/10.3389/fmicb.2017.02489