Multiple Myeloma-Derived Exosomes Regulate the Functions of Mesenchymal Stem Cells Partially via Modulating miR-21 and miR-146a

Exosomes derived from cancer cells can affect various functions of mesenchymal stem cells (MSCs) via conveying microRNAs (miRs). miR-21 and miR-146a have been demonstrated to regulate MSC proliferation and transformation. Interleukin-6 (IL-6) secreted from transformed MSCs in turn favors the surviva...

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Detalles Bibliográficos
Autores principales: Cheng, Qian, Li, Xin, Liu, Jingru, Ye, Qinmao, Chen, Yanfang, Tan, Sanqin, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733127/
https://www.ncbi.nlm.nih.gov/pubmed/29333170
http://dx.doi.org/10.1155/2017/9012152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733127/
https://www.ncbi.nlm.nih.gov/pubmed/29333170
http://dx.doi.org/10.1155/2017/9012152

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