Protective Effects of Garlic-Derived S-Allylmercaptocysteine on IL-1β-Stimulated Chondrocytes by Regulation of MMPs/TIMP-1 Ratio and Type II Collagen Expression via Suppression of NF-κB Pathway

BACKGROUND: Garlic-derived S-allylmercaptocysteine (SAMC) has widely been used in many disease therapies. However, the potential effects and mechanism of SAMC on IL-1β-stimulated chondrocytes are unclear. METHODS: Chondrocytes were isolated, and 5 ng/mL of IL-1β was added to mimic the in vitro osteo...

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Detalles Bibliográficos
Autores principales: Yang, Guang, Li, Siying, Li, Bin, Cheng, Lin, Jiang, Peng, Tian, Zhoubin, Sun, Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733130/
https://www.ncbi.nlm.nih.gov/pubmed/29333456
http://dx.doi.org/10.1155/2017/8686207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733130/
https://www.ncbi.nlm.nih.gov/pubmed/29333456
http://dx.doi.org/10.1155/2017/8686207

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