Salidroside Inhibits HMGB1 Acetylation and Release through Upregulation of SirT1 during Inflammation

HMGB1, a highly conserved nonhistone DNA-binding protein, plays an important role in inflammatory diseases. Once released to the extracellular space, HMGB1 acts as a proinflammatory cytokine that triggers inflammatory reaction. Our previous study showed that salidroside exerts anti-inflammatory effe...

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Detalles Bibliográficos
Autores principales: Qi, Zhilin, Zhang, Yao, Qi, Shimei, Ling, Liefeng, Gui, Lin, Yan, Liang, Lv, Jun, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733170/
https://www.ncbi.nlm.nih.gov/pubmed/29333216
http://dx.doi.org/10.1155/2017/9821543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733170/
https://www.ncbi.nlm.nih.gov/pubmed/29333216
http://dx.doi.org/10.1155/2017/9821543

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