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Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) ranks as the third leading cause of cancer-related mortality in China with increasing incidence. This study is designed to explore early genetic changes implicated in HCC tumorigenesis and progression by whole-exome sequencing. METHODS: We firstly sequenced...

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Detalles Bibliográficos
Autores principales: Zhan, Hao, Jiang, Jiahao, Sun, Qiman, Ke, Aiwu, Hu, Jinwu, Hu, Zhiqiang, Zhu, Kai, Luo, Chubin, Ren, Ning, Fan, Jia, Zhou, Jian, Huang, Xiaowu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733245/
https://www.ncbi.nlm.nih.gov/pubmed/29333154
http://dx.doi.org/10.1155/2017/2029315