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A Method for the Acute and Rapid Degradation of Endogenous Proteins

Methods for the targeted disruption of protein function have revolutionized science and greatly expedited the systematic characterization of genes. Two main approaches are currently used to disrupt protein function: DNA knockout and RNA interference, which act at the genome and mRNA level, respectiv...

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Detalles Bibliográficos
Autores principales: Clift, Dean, McEwan, William A., Labzin, Larisa I., Konieczny, Vera, Mogessie, Binyam, James, Leo C., Schuh, Melina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733393/
https://www.ncbi.nlm.nih.gov/pubmed/29153837
http://dx.doi.org/10.1016/j.cell.2017.10.033