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Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver
BACKGROUND & AIMS: Hepatitis B virus (HBV) infects hepatocytes, but the mechanisms of the immune response against the virus and how it affects disease progression are unclear. METHODS: We performed studies with BALB/c Rag2(–/–)Il2rg(–/–)Sirpa(NOD)Alb-uPA(tg/tg) mice, stably engrafted with human...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
W.B. Saunders
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733397/ https://www.ncbi.nlm.nih.gov/pubmed/28851562 http://dx.doi.org/10.1053/j.gastro.2017.08.034 |