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Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver

BACKGROUND & AIMS: Hepatitis B virus (HBV) infects hepatocytes, but the mechanisms of the immune response against the virus and how it affects disease progression are unclear. METHODS: We performed studies with BALB/c Rag2(–/–)Il2rg(–/–)Sirpa(NOD)Alb-uPA(tg/tg) mice, stably engrafted with human...

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Detalles Bibliográficos
Autores principales:	Dusséaux, Mathilde, Masse-Ranson, Guillemette, Darche, Sylvie, Ahodantin, James, Li, Yan, Fiquet, Oriane, Beaumont, Elodie, Moreau, Pierrick, Rivière, Lise, Neuveut, Christine, Soussan, Patrick, Roingeard, Philippe, Kremsdorf, Dina, Di Santo, James P., Strick-Marchand, Helene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	W.B. Saunders 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733397/ https://www.ncbi.nlm.nih.gov/pubmed/28851562 http://dx.doi.org/10.1053/j.gastro.2017.08.034

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