Accuracy of Programs for the Determination of Human Leukocyte Antigen Alleles from Next-Generation Sequencing Data

The human leukocyte antigen (HLA) genes code for proteins that play a central role in the function of the immune system by presenting peptide antigens to T cells. As HLA genes show extremely high genetic polymorphism, HLA typing at the allele level is demanding and is based on DNA sequencing. Determ...

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Detalles Bibliográficos
Autores principales: Larjo, Antti, Eveleigh, Robert, Kilpeläinen, Elina, Kwan, Tony, Pastinen, Tomi, Koskela, Satu, Partanen, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733459/
https://www.ncbi.nlm.nih.gov/pubmed/29326702
http://dx.doi.org/10.3389/fimmu.2017.01815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733459/
https://www.ncbi.nlm.nih.gov/pubmed/29326702
http://dx.doi.org/10.3389/fimmu.2017.01815

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