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Accuracy of Programs for the Determination of Human Leukocyte Antigen Alleles from Next-Generation Sequencing Data
The human leukocyte antigen (HLA) genes code for proteins that play a central role in the function of the immune system by presenting peptide antigens to T cells. As HLA genes show extremely high genetic polymorphism, HLA typing at the allele level is demanding and is based on DNA sequencing. Determ...
Autores principales: | Larjo, Antti, Eveleigh, Robert, Kilpeläinen, Elina, Kwan, Tony, Pastinen, Tomi, Koskela, Satu, Partanen, Jukka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733459/ https://www.ncbi.nlm.nih.gov/pubmed/29326702 http://dx.doi.org/10.3389/fimmu.2017.01815 |
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