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Thermo-Sensitive TRP Channels: Novel Targets for Treating Chemotherapy-Induced Peripheral Pain
Abnormal Ca(2+) channel physiology, expression levels, and hypersensitivity to heat have been implicated in several pain states following treatment with chemotherapeutic agents. As members of the Ca(2+) permeable transient receptor potential (TRP), five of the channels (TRPV1-4 and TRPM2) are activa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733463/ https://www.ncbi.nlm.nih.gov/pubmed/29326595 http://dx.doi.org/10.3389/fphys.2017.01040 |