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Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two age-dependent multifactorial neurodegenerative disorders, which are typically characterized by the selective death of motor neurons and cerebral cortex neurons, respectively. These two diseases share many clinical, genetic...

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Detalles Bibliográficos
Autores principales: Guo, Wenting, Fumagalli, Laura, Prior, Robert, Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733489/
https://www.ncbi.nlm.nih.gov/pubmed/29326542
http://dx.doi.org/10.3389/fnins.2017.00671