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A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism

Mutations and translocations within the COMPASS (complex of proteins associated with Set1) family of histone lysine methyltransferases are associated with a large number of human diseases, including cancer. Here we report that SET1B/COMPASS, which is essential for cell survival, surprisingly has a c...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Collings, Clayton K., Zhao, Zibo, Cozzolino, Kira Alia, Ma, Quanhong, Liang, Kaiwei, Marshall, Stacy A., Sze, Christie C., Hashizume, Rintaro, Savas, Jeffrey Nicholas, Shilatifard, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733497/
https://www.ncbi.nlm.nih.gov/pubmed/29138278
http://dx.doi.org/10.1101/gad.306092.117