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Orchestrated positioning of post-transcriptional modifications at the branch point recognition region of U2 snRNA

The branch point recognition region of spliceosomal snRNA U2 is heavily modified post-transcriptionally in most eukaryotic species. We focused on this region to learn how nearby positions may interfere with each other when targeted for modification. Using an in vivo yeast Saccharomyces cerevisiae ce...

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Detalles Bibliográficos
Autores principales: Deryusheva, Svetlana, Gall, Joseph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733568/
https://www.ncbi.nlm.nih.gov/pubmed/28974555
http://dx.doi.org/10.1261/rna.063842.117