Sbp1 modulates the translation of Pab1 mRNA in a poly(A)- and RGG-dependent manner

RNA-binding protein Sbp1 facilitates the decapping pathway in mRNA metabolism and inhibits global mRNA translation by an unclear mechanism. Here we report molecular interactions responsible for Sbp1-mediated translation inhibition of mRNA encoding the polyadenosine-binding protein (Pab1), an essenti...

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Detalles Bibliográficos
Autores principales: Brandariz-Núñez, Alberto, Zeng, Fuxing, Lam, Quan Ngoc, Jin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733569/
https://www.ncbi.nlm.nih.gov/pubmed/28986506
http://dx.doi.org/10.1261/rna.062547.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733569/
https://www.ncbi.nlm.nih.gov/pubmed/28986506
http://dx.doi.org/10.1261/rna.062547.117

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