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Non-Watson–Crick RNA synthesis suited to origin functions
A templated RNA synthesis is characterized in which G(5′)pp(5′)G accelerates synthesis of A(5′)pp(5′)A from pA and chemically activated ImpA precursors. Similar acceleration is not observable in the presence of UppU, CppC, AppG, AppA, or pG alone. Thus, it seems likely that AppA is templated by GppG...
Autores principales: | Puthenvedu, Deepa, Majerfeld, Irene, Yarus, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733574/ https://www.ncbi.nlm.nih.gov/pubmed/29042506 http://dx.doi.org/10.1261/rna.063974.117 |
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