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The TRPC1 Ca(2+)-permeable channel inhibits exercise-induced protection against high-fat diet-induced obesity and type II diabetes

The transient receptor potential canonical channel-1 (TRPC1) is a Ca(2+)-permeable channel found in key metabolic organs and tissues, including the hypothalamus, adipose tissue, and skeletal muscle. Loss of TRPC1 may alter the regulation of cellular energy metabolism resulting in insulin resistance...

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Detalles Bibliográficos
Autores principales: Krout, Danielle, Schaar, Anne, Sun, Yuyang, Sukumaran, Pramod, Roemmich, James N., Singh, Brij B., Claycombe-Larson, Kate J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733613/
https://www.ncbi.nlm.nih.gov/pubmed/29074621
http://dx.doi.org/10.1074/jbc.M117.809954