Stimulation of Alpha7 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Upregulation of MMP, MCP-1, and RANTES through Modulating ERK1/2/AP-1 Signaling Pathway in RAW264.7 and MOVAS Cells

Vagus nerve stimulation through alpha7 nicotine acetylcholine receptors (α7-nAChR) signaling had been demonstrated attenuation of inflammation. This study aimed to determine whether PNU-282987, a selective α7-nAChR agonist, affected activities of matrix metalloproteinase (MMP) and inflammatory cytok...

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Detalles Bibliográficos
Autores principales: Liu, Liping, Wu, Hongxian, Cao, Qunan, Guo, Zhenzhen, Ren, Anmin, Dai, Qiuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733626/
https://www.ncbi.nlm.nih.gov/pubmed/29348704
http://dx.doi.org/10.1155/2017/2401027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733626/
https://www.ncbi.nlm.nih.gov/pubmed/29348704
http://dx.doi.org/10.1155/2017/2401027

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