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A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis

INTRODUCTION: Steroid-resistant focal segmental glomerulosclerosis (SR-FSGS) is a common glomerulopathy associated with nephrotic range proteinuria. Treatment goals are reduction in proteinuria, which can delay end-stage renal disease. METHODS: Patients with SR-FSGS were enrolled in a randomized, do...

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Detalles Bibliográficos
Autores principales: Vincenti, Flavio, Fervenza, Fernando C., Campbell, Kirk N., Diaz, Montserrat, Gesualdo, Loreto, Nelson, Peter, Praga, Manuel, Radhakrishnan, Jai, Sellin, Lorenz, Singh, Ajay, Thornley-Brown, Denyse, Veronese, Francisco Veríssimo, Accomando, Beverly, Engstrand, Sara, Ledbetter, Steven, Lin, Julie, Neylan, John, Tumlin, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733825/
https://www.ncbi.nlm.nih.gov/pubmed/29270487
http://dx.doi.org/10.1016/j.ekir.2017.03.011