Gene Therapy for Color Blindness

Achromatopsia is a rare congenital cause of vision loss due to isolated cone photoreceptor dysfunction. The most common underlying genetic mutations are autosomal recessive changes in CNGA3, CNGB3, GNAT2, PDE6H, PDE6C, or ATF6. Animal models of Cnga3, Cngb3, and Gnat2 have been rescued using AAV gen...

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Detalles Bibliográficos
Autores principales: Hassall, Mark M., Barnard, Alun R., MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733843/
https://www.ncbi.nlm.nih.gov/pubmed/29259520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733843/
https://www.ncbi.nlm.nih.gov/pubmed/29259520

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