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Association between the APOE ε4 Allele and Late-Onset Alzheimer's Disease in an Ecuadorian Mestizo Population

Alzheimer's disease (AD) is the most common neurodegenerative disease. It has two main pathological hallmarks: amyloid plaques and neurofibrillary tangles. The APOE ε4 allele has been recognized as the strongest genetic risk factor for late-onset Alzheimer's disease (LOAD) in several popul...

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Detalles Bibliográficos
Autores principales: Montufar, Stefany, Calero, Cristian, Vinueza, Rodrigo, Correa, Patricio, Carrera-Gonzalez, Andrea, Villegas, Franklin, Moreta, Germania, Paredes, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733981/
https://www.ncbi.nlm.nih.gov/pubmed/29348964
http://dx.doi.org/10.1155/2017/1059678