Cargando…

Association between the APOE ε4 Allele and Late-Onset Alzheimer's Disease in an Ecuadorian Mestizo Population

Alzheimer's disease (AD) is the most common neurodegenerative disease. It has two main pathological hallmarks: amyloid plaques and neurofibrillary tangles. The APOE ε4 allele has been recognized as the strongest genetic risk factor for late-onset Alzheimer's disease (LOAD) in several popul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Montufar, Stefany, Calero, Cristian, Vinueza, Rodrigo, Correa, Patricio, Carrera-Gonzalez, Andrea, Villegas, Franklin, Moreta, Germania, Paredes, Rosario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733981/ https://www.ncbi.nlm.nih.gov/pubmed/29348964 http://dx.doi.org/10.1155/2017/1059678

Ejemplares similares

A flute player´s album of ecuadorian mestizo music : flute and piano, Vol. 1-2 /

Genotyping the High Altitude Mestizo Ecuadorian Population Affected with Prostate Cancer
por: López-Cortés, Andrés, et al.
Publicado: (2017)

Association of APOE Serum Levels and APOE ε2, ε3, and ε4 Alleles with Optic Neuritis
por: Momkute, Liucija, et al.
Publicado: (2022)

Intercultural Childbirth: Impact on the Maternal Health of the Ecuadorian Kichwa and Mestizo People of the Otavalo Region
por: Matute, Susana Eulalia Dueñas, et al.
Publicado: (2021)

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles
por: Walker, Rosie M., et al.
Publicado: (2021)

Case report: Genomic screening for inherited cardiac conditions in Ecuadorian mestizo relatives: Improving familial diagnose
por: Cadena-Ullauri, Santiago, et al.
Publicado: (2022)

Modic Changes in Ecuadorian Mestizo Patients: Epidemiology, Clinical Significance, and Role in Chronic Low Back Pain
por: Sornoza, Kléver Eduardo, et al.
Publicado: (2023)

Updated meta-analysis of the role of APOE ε2/ε3/ε4 alleles in frontotemporal lobar degeneration
por: Su, Wen-Hua, et al.
Publicado: (2017)

APOE ε4, an Alzheimer’s disease susceptibility allele, and smoking cessation
por: Ashare, Rebecca L., et al.
Publicado: (2012)

Effect of APOE ε4 allele on survival and fertility in an adverse environment
por: van Exel, Eric, et al.
Publicado: (2017)

Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia
por: Salvadó, Gemma, et al.
Publicado: (2021)

Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers
por: Kulminski, Alexander M., et al.
Publicado: (2022)

Reduced Physiological Complexity in Robust Elderly Adults with the APOE ε4 Allele
por: Cheng, Daniel, et al.
Publicado: (2009)

Salivary MicroRNAs for Early Detection of Head and Neck Squamous Cell Carcinoma: A Case-Control Study in the High Altitude Mestizo Ecuadorian Population
por: Salazar-Ruales, Carolina, et al.
Publicado: (2018)

Mutational Analysis of Oncogenic AKT1 Gene Associated with Breast Cancer Risk in the High Altitude Ecuadorian Mestizo Population
por: López-Cortés, Andrés, et al.
Publicado: (2018)

The ε3 and ε4 Alleles of Human APOE Differentially Affect Tau Phosphorylation in Hyperinsulinemic and Pioglitazone Treated Mice
por: To, Alvina W. M., et al.
Publicado: (2011)

Dissecting the Gene Dose-Effects of the APOE ε4 and ε2 Alleles on Hippocampal Volumes in Aging and Alzheimer’s Disease
por: Hostage, Christopher A., et al.
Publicado: (2013)

Association of Pancreatic Polypeptide with Mild Cognitive Impairment Varies by APOE ε4 Allele
por: Roberts, Rosebud O., et al.
Publicado: (2015)

Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers
por: Martiskainen, Henna, et al.
Publicado: (2018)

THE APOE-ε4 ALLELE AND AGE SYNERGISTICALLY DRIVE DISEASE PROGRESSION IN ALZHEIMER’S DISEASE
por: Kleineidam, Luca, et al.
Publicado: (2019)

APOE-ε4 Allele Altered the Rest-Stimulus Interactions in Healthy Middle-Aged Adults
por: Yan, Feng-Xian, et al.
Publicado: (2015)

Possible positive effect of the APOE ε2 allele on cognition in early to mid-adult life
por: Sinclair, Lindsey I., et al.
Publicado: (2017)

The Effect of the APOE-ε4 Allele on the Cholinergic Circuitry for Subjects With Different Levels of Cognitive Impairment
por: Lai, Ying-Liang Larry, et al.
Publicado: (2021)

Effects of APOE ε2 allele on basal forebrain functional connectivity in mild cognitive impairment
por: Liu, Xiaocao, et al.
Publicado: (2022)

Correlation Between Amygdala Nuclei Volumes and Memory in Cognitively Normal Adults Carrying the ApoE ε3/ε3 Allele
por: Liao, Wenqing, et al.
Publicado: (2021)

Constitucionalismo mestizo /
por: Sáchica, Luis Carlos
Publicado: (2002)

Novel domain-specific POU3F4 mutations are associated with X-linked deafness: examples from different populations
por: Bademci, Guney, et al.
Publicado: (2015)

ε2 allele and ε2-involved genotypes (ε2/ε2, ε2/ε3, and ε2/ε4) may confer the association of APOE genetic polymorphism with risks of nephropathy in type 2 diabetes: a meta-analysis
por: Shi, Jikang, et al.
Publicado: (2020)

APOE ε4 allele, along with G206D-PSEN1 mutation, alters mitochondrial networks and their degradation in Alzheimer’s disease
por: Costa-Laparra, Irene, et al.
Publicado: (2023)

Corrigendum: Correlation between amygdala nuclei volumes and memory in cognitively normal adults carrying the ApoE ε3/ε3 allele
por: Liao, Wenqing, et al.
Publicado: (2022)

Frequency Specific Effects of ApoE ε4 Allele on Resting-State Networks in Nondemented Elders
por: Liang, Ying, et al.
Publicado: (2017)

APOE ε4 Allele Is Associated with Elevated Levels of CSF VILIP-1 in Preclinical Alzheimer’s Disease
por: Wang, Lijun, et al.
Publicado: (2020)

The APOE ε4 allele in relation to pre‐ and postsurgical cognitive functioning of patients with primary brain tumors
por: Butterbrod, Elke, et al.
Publicado: (2021)

Genetic association between the APOE ε4 allele, toxicant exposures and Gulf war illness diagnosis
por: Abdullah, L, et al.
Publicado: (2023)

APOE ε4-Allele in Middle-Aged and Older Autistic Adults: Associations with Verbal Learning and Memory
por: Harker, Samantha A., et al.
Publicado: (2023)

Interaction between KLOTHO-VS Heterozygosity and APOE ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer’s Disease
por: Chen, Xi Richard, et al.
Publicado: (2023)

Prevalence and Diversity of Salmonella Serotypes in Ecuadorian Broilers at Slaughter Age
por: Vinueza-Burgos, Christian, et al.
Publicado: (2016)

El pensamiento mestizo /
por: Gruzinski, Serge
Publicado: (2000)

Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele
por: Padayachee, E.R., et al.
Publicado: (2016)

Patients with Alzheimer's disease who carry the APOE ε4 allele benefit more from physical exercise
por: Jensen, Camilla Steen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1akao7avhqhubd42clr2u9iauf