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Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer’s Disease

BACKGROUND: Abnormal insulin signaling in the brain has been linked to Alzheimer’s disease (AD). OBJECTIVE: To evaluate whether cerebrospinal fluid (CSF) insulin levels are associated with cognitive performance and CSF amyloid-β and Tau. Additionally, we explore whether any such association differs...

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Detalles Bibliográficos
Autores principales: Geijselaers, Stefan L.C., Aalten, Pauline, Ramakers, Inez H.G.B., De Deyn, Peter Paul, Heijboer, Annemieke C., Koek, Huiberdina L., OldeRikkert, Marcel G.M., Papma, Janne M., Reesink, Fransje E., Smits, Lieke L., Stehouwer, Coen D.A., Teunissen, Charlotte E., Verhey, Frans R.J., van der Flier, Wiesje M., Biessels, Geert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734123/
https://www.ncbi.nlm.nih.gov/pubmed/29154275
http://dx.doi.org/10.3233/JAD-170522